PhD position in Engineering/Natural Sciences (Bremen - Germany)

Development of an MRI-based in-vivo method for the quantification of reactant gradients, mass transfer characteristics, and biomass growth in productive biofilms

Aim of this project is to further develop Magnetic Resonance Imaging (MRI) as an in vivo/in situ technique for investigating the spatial distribution of biomass density, mass transfer properties, substrate (O2 and H2) and pH gradients in biofilms and determine their influence on reaction rates and biomass growth. Using different MR techniques, the morphology as well as the spatially resolved pH, O2 and H2 concentrations within the biofilm will be characterized. Furthermore, locally resolved effective diffusion coefficients within the biofilm will be determined. In the end, we will expose the biofilms of C. necator to quorum sensing molecules and use our MRI method to dynamically investigate their effects on architecture and productivity as a function of local pH and oxygen conditions. The project is part of the DFG’s Priority Programme “Productive Biofilm Systems” (SPP 2494) and the position is integrated into the Research Group Environmental Process Engineering (Prof. Dr.-Ing. S. Kerzenmacher). It will be co-supervised by Dr. E. Küstermann (in-vivo MR) and Dr. C. Roggatz (Research Group Dynamic Ecological Chemistry).

How to apply

Please send your application documents until December 31st 2025 via email as one compiled pdf document to Prof. S. Kerzenmacher (kerzenmacher@uni-bremen.de). It should contain your Academic CV (including list of publications if applicable), copies of BSc/ MSc degree transcripts and certificates (as well as work references if applicable), the contact information for 2 referees, and a Statement of Interest (1-page maximum) detailing specifically what motivated you to apply for the position, why you are interested in the proposed research topic and outlining your skills and experience that fit the post. For further information and in case of questions, please do not hesitate to contact Prof. Kerzenmacher directly using the above email address.

More info: https://www.uni-bremen.de/en/uvt/jobs/phd-position-m-f-d-in-engineering-natural-sciences